Description
Biochem/physiol Actions Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.
Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
Legal Information Chloromycetin is a registered trademark of Parke-Davis & Co.
Properties
assay ≥98% (TLC)
mp 148-150 °C(lit.)
Gene Information human ... CYP1A2(1544)
Safety
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes T
Risk Statements 45
Safety Statements 53-45
WGK Germany 3
RTECS AB6825000