抗菌肽CAMP抗體 Anti-Cathelicidin抗體相關(guān)標(biāo)記     Alexa Fluor 350   Alexa Fluor 488   Alexa Fluor 555   Alexa Fluor 647   AP  APC   Biotin   Cy3   Cy5  
 Cy5.5   Cy7   FITC   Gold   HRP   PE   PE-Cy3   PE-CY5   PE-CY5.5   PE-CY7  RBITC  
英文名稱     Anti-Cathelicidin
中文名稱     抗菌肽CAMP抗體
別    名     18 kDa cationic antimicrobial protein; Antibacterial protein FALL-39; Antibacterial protein LL-37; CAMP; CRAMP_MOUSE; CAP 18; CAP-18; CAP18; cathelicidin antimicrobial peptide; Cathelicidin antimicrobial peptide precursor; Cathelin-like protein; Cathelin-related antimicrobial peptide; CATHL3; Cationic antimicrobial protein CAP 18; Cationic antimicrobial protein, 18-KD; CLP; Cnlp; Cramp; CRAMP, mouse, homolog of; FALL 39; FALL 39 peptide antibiotic; FALL-39 peptide antibiotic; FALL39; hCAP 18; hCAP-18; hCAP18; HSD26; LL 37; LL37; MCLP; mcramp; Peptide antibiotic, PR-39, porcine, homolog of; SOB3.
抗體來源     Rabbit
克隆類型     polyclonal
交叉反應(yīng)     Mouse, Rat, 
產(chǎn)品類型     一抗  
研究領(lǐng)域     細(xì)胞生物 免疫學(xué) 微生物學(xué) 細(xì)菌及病毒
蛋白分子量     predicted molecular weight: 4kDa
性    狀     Lyophilized or Liquid
免 疫 原     KLH conjugated synthetic peptide derived from mouse Cathelicidin
亞    型     IgG
純化方法     affinity purified by Protein A
儲(chǔ) 存 液     Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
抗菌肽CAMP抗體 Anti-Cathelicidin抗體產(chǎn)品應(yīng)用      ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
（石蠟切片需做抗原修復(fù)） 

 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.
保存條件     Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note     This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
抗體產(chǎn)品介紹    Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils. Along with the family of proteins known as defensins, cathelicidins participate in the first line of defense by preventing local infection and systemic invasion of microbes. FALL-39 precursor (FALL-39 peptide antibiotic, cationic anti-microbial protein, CAMP, CAP-18, HSD26) is a cathelicidin anti-microbial protein that contains the antibacterial peptide LL-37 (amino acids 134-170). In contrast to the defensins, which are cysteine-rich peptides that fold in ∫-pleated sheets, LL-37 is a cysteine-free peptide that can adopt an amphipathic å-helical conformation. LL-37 binds to bacterial lipopolysaccharides (LPS) and is a potent chemotactic factor for recruiting mast cells to sites of inflammation. LL-37 is present in inflammatory skin diseases that include psoriasis, sub-acute lupus erthematosus, dermatitis and nickel contact hypersensitivity. It is not found in normal skin epidermis. The secreted protein is expressed primarily in bone marrow, testis and neutrophils. The mouse and rat ortholog, CRAMP (cathelin-related antimicrobial peptide), is also part of the cathelicidin family of host defense peptides. These include precursors of potent antimicrobial peptides that direct antimicrobial activity against various microbial pathogens and also activate mesenchymal cells during wound repair. CRAMP is expressed in testis, spleen, stomach and intestine.
Function : Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
Subcellular Location : Secreted.
Tissue Specificity : Expressed in bone marrow and testis and neutrophils.
Similarity : Belongs to the cathelicidin family.
Database links : UniProtKB/Swiss-Prot: P51437.1