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更新時(shí)間：2018-05-18 20:00:01瀏覽次數(shù)：305次
聯(lián)系我時(shí)，請(qǐng)告知來(lái)自 環(huán)保在線博研生物強(qiáng)烈*“Anti-Rad53/SPK1抗體,*蛋白激酶1抗體-實(shí)驗(yàn)室"，品質(zhì)保障，*，提供，實(shí)驗(yàn)無(wú)結(jié)果可免費(fèi)退換?。?/p>
Anti-Rad53/SPK1抗體,*蛋白激酶1抗體-實(shí)驗(yàn)室產(chǎn)品介紹：In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Several transcript variants encoding different isoforms have been found for this gene.
保存條件: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
重要提示: 本產(chǎn)品提供僅供研究使用，不用于人類治療或診斷.
產(chǎn)品名稱：Anti-Rad53/SPK1抗體,*蛋白激酶1抗體-實(shí)驗(yàn)室
產(chǎn)品編號(hào)：BYK-11792R
產(chǎn)品規(guī)格：0.1ml/0.2ml
產(chǎn)品價(jià)格：請(qǐng)
性 狀：Lyophilized or Liquid
濃 度：1mg/1ml
亞 型：IgG
貯 存：貯存于-20℃.
抗體來(lái)源：本公司抗體有兔來(lái)源和鼠來(lái)源等
克隆類型：兔來(lái)源為多抗，鼠來(lái)源為單抗
產(chǎn)品類型：一抗
此抗體本公司有單抗和多抗，可用于免疫組化（IHC），免疫印跡（WB），酶聯(lián)免疫(ELISA)，IF、IP、流式細(xì)胞術(shù)等實(shí)驗(yàn)（可來(lái)電索取說(shuō)明）
此產(chǎn)品本公司有標(biāo)記的一抗出售，相關(guān)標(biāo)記有：Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記
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