HCLS1,造血干細胞特異性蛋白產(chǎn)品詳情：
英文名稱：HCLS1 Peptide
中文名稱：造血干細胞特異性蛋白
產(chǎn)品編號：byk-0125P
規(guī) 格：0.5mg
多肽活性：多肽
產(chǎn)品來源：合成
分 類：小分子偶聯(lián)物
偶聯(lián)蛋白：KLH
純化方法：HPLC
儲 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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保存條件：Store at -20 °C for one year. The lyophilized powder is stable at room temperature for at least one month and for greater than a year when kept at -20°C. Upon reconstituted, aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹：Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. Subunit : Associates with the SH2 and SH3 domains of LCK. Binding to he LCK SH3 domain occurs constitutively, while binding to the LCK SH2 domain occurs only upon TCR stimulation. A similar binding pattern was observed with LYN, but not with FYN in which the FYN SH2 region associates upon TCR stimulation but the FYN SH3 region does not associate regardless of TCR stimulation. Directly associates with HAX1, through binding to its C-terminal region. Interacts with HS1BP3. Interacts with FES/FPS. Interacts (via SH2 domain) with FGR. Forms a multiprotein complex with LYN and ANKRD54
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