Anti-XAF1 （XIAP-associated factor 1） 抗體說(shuō)明書(shū)
Catalog Number :Rs-1308R
Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Background: X-linked inhibitor of apoptosis （XIAP; MIM 300079） is a potent member of the IAP family. All members of this family possess baculoviral IAP （BIR） repeats, cysteine-rich domains of approximay 80 amino acids that bind and inhibit caspases（e.g., CASP3; MIM 600636）. XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase （see MIM 601623） activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells
Anti-XAF1 （XIAP-associated factor 1） 抗體說(shuō)明書(shū)
Specificity : · anti- XAF1 is a Rabbit monoclonal antibody unconjugated
· specific for XAF1 of hu, mo, rat,
· epitope mapping near the N-terminus of XAF1 of hu, mo, rat
· use for western blotting, elisa, immunoprecipitation
and immunohistochemistry
· Protein G affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt:32kDa
Application: · Western blotting 1:100-500
· Immunohistochemistry 1:100-500
· ELISA 1:500-1000
· Optimal working dilutions must be determined by the end user.
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Anti-XAF1 （XIAP-associated factor 1） 抗體說(shuō)明書(shū)
