Rabbit Anti- ARID1A
Catalog Number : RS-20149R
Quantity size : 0.2ml (dilute with pH 7.4 0.01 M PBS or antibody diluent )
Background: :Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Binds DNA non-specifically. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex).
Specificity : · anti-ARID1A is a rabbit monoclonal antibody unconjugated
· specific for ARID1A of hu, rat, mo
· epitope mapping in the C-terminalse of ARID1A of hu, rat, mo
· use for western blotting, elisa, immunoprecipitation and immunohistochemistry
· Protein G affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt: 34kDa
Rabbit Anti- ARID1A
Application: ·Western blotting 1:100-500
·Immunohistochemistry 1:100-500
·ELISA 1:500-1000
·Optimal working dilutions must be determined by the end user.
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rabbit Anti- ARID1A