Rabbit Anti-Annexin II
FROM:Abcam
Catalog Number : RS-0576R
Quantity size : 0.2ml (dilute with pH 7.4 0.01 M PBS or antibody diluent )
Background: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin II is a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specificity :
– anti-Annexin II is a rabbit monoclonal antibody unconjugated
– specific for Annexin II of Pig
– epitope mapping near the amino term inus of Annexin II of Pig
– use for elisa, immunoprecipitation and immunohistochemistry
– Protein G affinity chromatogr aphy purification, purity :>95%
– Isotype: IgG
– mol wt: 120kDa
Rabbit Anti-Annexin II
Application :
– Immunohistochemistry 1:100-500
– ELISA 1:500-1000
– Optimal working dilutions must be determined by the end user.
Storage:
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃.
Important Note:
This product as supplied is intended for research use only, not for use in therapeutic or diagnostic applications.
Rabbit Anti-Annexin II