Rabbit Anti-MMP-9
FROM: ABCAM
Catalog Number : RS-0397R
Quantity size : 0.2ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Background: All cells within tissues are surrounded by an extracellular matrix （ECM） giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases （MMPs）, are involved in the modulation of cell matrix interactions. MMPs are Zn（2+） binding endopeptidases that degrade various components of the ECM. MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion. These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs （tissue inhibitors of matrix metalloproteinases）. TIMPs have been shown to block tumor cell invasion suggesting that they act as metastasis suppressor genes.
Specificity : · anti- MMP-9 is a rabbit monoclonal antibody unconjugated
· specific for MMP-9 of hu, rat, mo
· epitope mapping in the C-terminalse of MMP-9 of hu, rat, mo
· use for western blotting, elisa, immunoprecipitation and immunohistochemistry
· Protein G affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt: 34kDa
Rabbit Anti-MMP-9
Application: ·Western blotting 1:100-500
·Immunohistochemistry 1:100-500
·ELISA 1:500-1000
·Optimal working dilutions must be determined by the end user.
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rabbit Anti-MMP-9
