Anti-Histone H3-like protein 組蛋白H3樣抗體
專業(yè)提供Anti-Histone H3-like protein 組蛋白H3樣抗體,廣泛應用于免疫組化，ELISA，Western Blot IHC-F（免疫組化－冰凍切片），IHC-P （免疫組化－石蠟切片）IP（免疫沉淀）， Flow-Cyt等方面。
產品編號 Rs-0483R
英文名稱 Anti-Histone H3-like protein
中文名稱 組蛋白H3樣抗體
別 名 centromere-specific H3 variant protein.
抗體介紹：Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer （2 molecules of each）. Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications （the "histone code" hypothesis）. Trimethylation of histone H3 on Lys9 （H3K9me3） is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1α/β. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
產品類型 一抗 植物抗體
抗體來源 Rabbit
克隆號 Polyclonal
交叉反應 Brassica juncea
蛋白分子量 Predicted Molecular Weight: 20kDa
性狀 Lyophilized or Liquid
濃度 1mg/1ml
免疫原 KLH conjugated synthetic peptide derived from Brassica juncea Histone H3-like protein N-terminus.
亞型 IgG
研究領域 腫瘤 免疫學 發(fā)育生物學 轉錄調節(jié)因子 植物
公司提供的.已被國內外廣大科研工作者使用，廣泛用于分子生物學、免疫學等試驗中。
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