Anti-StAR 抗體說明書

【資料簡介】

Anti-StAR 抗體說明書

Quantity Size : 0.2ml （dilute with pH 7.4  0.01 M PBS or antibody diluent ）

Background: StAR plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. StAR permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia （CLAH）, also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode distinct isoforms.

Specificity :  · anti-StAR is a rabbit monoclonal antibody unconjugated

· specific for StAR of human, mouse, rat

· broadly reactive with mammalian species

· epitope mapping near the amino terminus of StAR of human, mouse, rat

· use for western blotting, elisa, immunoprecipitation

and immunohistochemistry

· Protein G affinity chromatography purification, purity :>95%

· Isotype: IgG

· mol wt: 32kDa

Application : · Western blotting 1:100-500

· Immunohistochemistry 1:100-500

· ELISA 1:500-1000

· Optimal working dilutions must be determined by the end user

Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Anti-StAR 抗體說明書