Anti-CD38抗體詳細(xì)說(shuō)明書

【資料簡(jiǎn)介】

產(chǎn)品類別     產(chǎn)品目錄 >>  一抗 >>  一抗
相關(guān)標(biāo)記     Alexa Fluor 350   Alexa Fluor 488   Alexa Fluor 555   Alexa Fluor 647   AP   APC   Biotin   Cy3   Cy5  
 Cy5.5   Cy7   FITC   Gold   HRP   PE   PE-Cy3   PE-CY5   PE-CY5.5   PE-CY7   RBITC  
英文名稱     Anti-CD38
中文名稱     CD38抗體
別    名     Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase 1; ADP ribosyl cyclase; ADP ribosyl cyclase/cyclic ADP-ribose hydrolase; CADPr hydrolase 1; CD 38; CD38 antigen; Cd38-rs1; CD38H; Cyclic ADP ribose hydrolase 1; I-19; Lymphocyte differentiation antigen CD38; NIM-R5 antigen; NIMR5 antigen (mouse); p45; T10.
濃    度     1mg/1ml
克隆類型     polyclonal
交叉反應(yīng)     Mouse, Rat, 
產(chǎn)品類型     一抗  
研究領(lǐng)域     腫瘤 免疫學(xué) 干細(xì)胞 糖尿病 細(xì)胞表面分子 自然殺傷細(xì)胞 淋巴細(xì)胞 t-淋巴細(xì)胞 b-淋巴細(xì)胞
蛋白分子量     predicted molecular weight: 34kDa
性    狀     Lyophilized or Liquid
免 疫 原     KLH conjugated synthetic peptide derived from mouse CD38 (101-150aa)
亞    型     IgG
純化方法     affinity purified by Protein A
儲(chǔ) 存 液     0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應(yīng)用      WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500 
（石蠟切片需做抗原修復(fù)）

 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.
保存條件     Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note     This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相關(guān)產(chǎn)品     免疫組化常用試劑    免疫印跡常用試劑    各種標(biāo)記二抗

產(chǎn)品介紹：
CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion, signal transduction and calcium signaling. CD38 antigen is an integral membrane glycoprotein, M.W. 45 kD. The CD38 antigen is present on approximay all pre-B lymphocytes, plasma cells and thymocytes. CD38 antigen is also expressed on activated T Lymphocytes, NK Cells, monocytes, myeloblasts and erythroblasts. CD38 is co-expressed on CD34+ cells,but is not expressed on pluripotent stem cells. CD38 antigen is present on T and B lymphoblastic leukemia (ALL), Burkitts' lymphoma, multiple myeloma and acute myeloid leukemia (AML).
Function : Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Subcellular Location : Membrane; Single-pass type II membrane protein.
Tissue Specificity : Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Similarity : Belongs to the ADP-ribosyl cyclase family.
CD38分子是單鏈Ⅱ型跨膜糖蛋白，存在于很多免疫細(xì)胞表面上,CD38與無(wú)脊椎動(dòng)物卵的授精、HIV感染、某些癌癥以及糖尿病等有關(guān)，CD38具有許多復(fù)雜而又*的生物學(xué)特性及功能，有調(diào)控細(xì)胞鈣釋放的機(jī)制。主要表達(dá)于胸腺細(xì)胞、前T和前B細(xì)胞、活化的T和B細(xì)胞、單核細(xì)胞、NK細(xì)胞、漿細(xì)胞等，可用于急性白血病的分型和活化的T細(xì)胞在自身免疫和免疫缺陷中的作用等方面的研究，也可作為生發(fā)中心B細(xì)胞的一種選擇性標(biāo)記。 
產(chǎn)品圖片    

Antigen: bs-0979P, 0.2ug/100ul 
Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; 
Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; 
TMB(C-0024) staining; 
Read the data in MicroplateReader by 450nm.