Rabbit Anti-PAR-2
（Protease-activated receptors-2）
Catalog Number : Rs-1178R
Quantity Size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Background: The Proteinase-activated receptor 2 （PAR2） is a member of the proteinase-activated receptor subfamily. It is activated through proteolytic exposure of an occult tethered ligand by trypsin and trypsin-like proteases. This is in contrast to other members of the subfamily which are activated by the protease thrombin. PAR2 has been implicated in acute inflammatory response, asthma, and pain transmission. PAR2 expression has been documented in the periphery. ESTs have been isolated from adrenal, brain, breast, heart/melanocyte/uterus, kidney, lung, and vessel libraries.
Specificity : · anti-Protease-activated receptors-2 is a rabbit monoclonal antibody unconjugated
· specific for Protease-activated receptors-2 of human, mouse, rat
· broadly reactive with mammalian species
·epitope mapping near the amino terminus of Protease-activated receptors-2 of human, mouse, rat
· use for western blotting, elisa, immunoprecipitation
and immunohistochemistry
· Protein G affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt: 43kDa
Rabbit Anti-PAR-2
Application : · Western blotting 1:100-500
· Immunohistochemistry 1:100-500
· ELISA 1:500-1000
· Optimal working dilutions must be determined by the end user
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rabbit Anti-PAR-2
