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上海瑞齊生物科技有限公司

Anti- APH-1抗體說明書

時(shí)間:2012-1-6閱讀:496
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 Anti- APH-1抗體說明書

Quantity size:0.1ml (dilute with pH 7.4 0.01 M PBS or diluent of antibody)
 
Background:The gamma secretase is a multiprotein complex consisting of presenilin,nicastrin, Aph-1 and Pen-2; all four proteins are necessary for full proteolytic activity. The gamma secretase complex catalyzes cleavage of a number of integral membrane proteins including Amyloid precursor protein, Notch, Erb4 and E-cadherin. While Aph-1 stabilizes the presenilin holoprotein within the gamma secretase complex, Pen-2 is required for endoproteolysis of presenilin and activation of the gamma secretase.
 

 Anti- APH-1抗體說明書

Specificity :  ·anti-APH-1 is a rabbit monoclonal antibody unconjugated
·specific for APH-1 of human, mouse, rat
·use for western blot, elisa, immunoprecipitation
and immunohistochemistry
·affinity chromatography purification, purity :>95%
·isotype: IgG
·mol wt: 91kDa
 
Application :· Immunohistochemistry: 1:100-500
· ELISA: 1:500-1000
· Western blotting 1:100-500
· Optimal working dilutions must be determined by the end user.
 
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ºC.
 
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 Anti- APH-1抗體說明書

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