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FGF-4人細(xì)胞生長(zhǎng)因子Recombinant Human FGF-4 返回列表頁

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生化試劑、抗體、血清: 特級(jí)胎牛血清化學(xué)發(fā)光底物 Abcam抗體實(shí)驗(yàn)耗材常規(guī)生化試劑血清/培養(yǎng)基試劑盒細(xì)胞因子抗體/蛋白

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Recombinant Human FGF-4 Synonyms:
Fibroblast Growth Factor-4, HST-1, transforming protein KS3, HBGF-4

詳情介紹

Description:

FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.

AA Sequence:

GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL

Source:

E.coli

Purity:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10⁶units/mg.

Cross Reactivity:

Mouse, Rat, Human, N/A, Pig

Research Interests: