名稱：現(xiàn)貨訂購|LY294002 （PI3 Kinase Inhibitor） 

貨號：9901
規(guī)格：1.5mg 
產(chǎn)地：CST
存儲溫度： -20ºC
Background
LY294002 （PI3 Kinase Inhibitor） was shown to act in vivo as a highly selective inhibitor of phosphatidylinositol 3 （PI3） kinase. Western blot analysis of extracts from PDGF, wortmannin and LY294002 treated NIH/3T3 cells, MAP kinase or c-Src （1）. LY294002 is soluble in DMSO or ethanol. When used at a concentration of 50 μM, it specifically abolished PI3 kinase activity （IC50=0.43 μg/ml; 1.40 μM） but did not inhibit other lipid and protein kinases such as PI4 kinase, PKC.
Directions for Use
For use with in vitro or cell-based assays, it may be diluted into aqueous buffers to yield the desired concentrations. For experiments with cultured cells, For 10 mM stock, reconstitute 1.5 mg in 488 µl DMSO. For 50 mM stock, reconstitute 1.5 mg in 98 µl DMSO. Store aliquots at -20ºC. LY294002 has been shown to block PI3 kinase-dependent Akt phosphorylation and kinase activity.